The two rappers recently teamed up on Snoop Dogg’s album ‘Missionary’

Curtis "50 Cent" Jackson and Eminem attend the ceremony honoring Curtis "50 Cent" with a Star on the Hollywood Walk of Fame on January 30, 2020

50 Cent and Eminem in January 2020. Photo: Axelle/Bauer-Griffin/FilmMagic

Another Eminem and 50 Cent team-up could be a possibility.

In an interview on Whoo’s House on SiriusXM’s Shade 45 from Saturday, Dec. 21, the “Without Me” rapper, 52, revealed that he’d be open to collaborating with the “In da Club” hitmaker, 49, on a full album — more than 20 years since the pair first worked together on “Patiently Waiting.”

“That would be great,” Eminem said. “We just gotta stop bulls—ting and just do it.”

Curtis "50 Cent" Jackson and Eminem attend the ceremony honoring Curtis "50 Cent" with a Star on the Hollywood Walk of Fame on January 30, 2020

50 Cent and Eminem in Hollywood in January 2020.Axelle/Bauer-Griffin/FilmMagic

He added: “I would never say it’s not possible.”

In 2014, the pair opened up about the making of “Patiently Waiting” on Complex’s “Magnum Opus.”

“’Patiently Waiting’ was one of the first beats I sent Fif,” Eminem told the outlet. “[It] just had the cello… the strings on it and the drums.”

50 Cent admired the raw production and seamlessly wrote music to it.

“It had enough for me to know the tempo and the feel of it,” he said. “And those words came out.”

While “Patiently Waiting” became one of the hits from the “Many Men” performer’s debut album Get Rich or Die Tryin’, which included tracks like “In Da Club,” “21 Questions” and “P.I.M.P,” it was never released as a single.

Eminem and 50 Cent recently teamed up for “Gunz N Smoke” alongside Dr. Dre on Snoop Dogg’s 2024 album Missionary.

50 Cent and Eminem

50 Cent in October 2024; Eminem in January 2020.

Al Pereira/Getty; Kurt Krieger/Corbis via Getty

Back in 2002, Eminem discovered 50 Cent and signed the “Candy Shop” artist to his Shady Records label. Since then, 50 Cent has become a massive success in music and on-screen. While Eminem has often pivoted between music, TV and touring, he has stayed laser-focused on music.

“He’s still in that pocket. He’s still doing the same thing, still drilling it, still number one, still highest selling. He can still do it. He can still hold it,” 50 Cent told PEOPLE in October.

He added: “That’s because he never stopped. He stayed right there. When I started looking at film and television and other areas to pivot, he stayed right in a recording studio recording.”